Wendell A. Lim: search on Z-Library

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1

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

Qi, Lei S., Larson, Matthew H., Gilbert, Luke A., Doudna, Jennifer A., Weissman, Jonathan S., Arkin, Adam P., Lim, Wendell A.

Journal:

Year:

2013

Language:

english

File:

PDF, 843 KB

english, 2013

2

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Gilbert, Luke A., Larson, Matthew H., Morsut, Leonardo, Liu, Zairan, Brar, Gloria A., Torres, Sandra E., Stern-Ginossar, Noam, Brandman, Onn, Whitehead, Evan H., Doudna, Jennifer A., Lim, Wendell A.,

Journal:

Year:

2013

Language:

english

File:

PDF, 689 KB

english, 2013

3

Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation

Dominguez, Antonia A., Lim, Wendell A., Qi, Lei S.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2015

Language:

english

File:

PDF, 748 KB

english, 2015

4

Domains, Motifs, and Scaffolds: The Role of Modular Interactions in the Evolution and Wiring of Cell Signaling Circuits

Bhattacharyya, Roby P., Reményi, Attila, Yeh, Brian J., Lim, Wendell A.

Journal:

Annual Review of Biochemistry

Year:

2006

Language:

english

File:

PDF, 2.34 MB

english, 2006

5

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

Larson, Matthew H, Gilbert, Luke A, Wang, Xiaowo, Lim, Wendell A, Weissman, Jonathan S, Qi, Lei S

Journal:

Nature Protocols

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

6

Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

Zalatan, Jesse G., Lee, Michael E., Almeida, Ricardo, Gilbert, Luke A., Whitehead, Evan H., La Russa, Marie, Tsai, Jordan C., Weissman, Jonathan S., Dueber, John E., Qi, Lei S., Lim, Wendell A.

Journal:

Year:

2015

Language:

english

File:

PDF, 662 KB

english, 2015

7

Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials

Esensten, Jonathan H., Bluestone, Jeffrey A., Lim, Wendell A.

Journal:

Annual Review of Pathology Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 935 KB

english, 2017

8

The Principles of Engineering Immune Cells to Treat Cancer

Lim, Wendell A., June, Carl H.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

9

Alternative packing arrangements in the hydrophobic core of λrepresser

Lim, Wendell A., Sauer, Robert T.

Journal:

Year:

1989

File:

PDF, 751 KB

1989

10

Engineering synthetic signaling proteins with ultrasensitive input/output control

Dueber, John E, Mirsky, Ethan A, Lim, Wendell A

Journal:

Nature Biotechnology

Year:

2007

Language:

english

File:

PDF, 209 KB

english, 2007

11

Synthetic biology: lessons from the history of synthetic organic chemistry

Yeh, Brian J, Lim, Wendell A

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 1.63 MB

english, 2007

12

Defining Network Topologies that Can Achieve Biochemical Adaptation

Wenzhe Ma, Ala Trusina, Hana El-Samad, Wendell A. Lim, Chao Tang

Journal:

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

13

Rewiring Cells: Synthetic Biology as a Tool to Interrogate the Organizational Principles of Living Systems

Bashor, Caleb J., Horwitz, Andrew A., Peisajovich, Sergio G., Lim, Wendell A.

Journal:

Annual Review of Biophysics

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010

14

Exploitation of Latent Allostery Enables the Evolution of New Modes of MAP Kinase Regulation

Coyle, Scott M., Flores, Jonathan, Lim, Wendell A.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.70 MB

english, 2013

15

Bridging cross-cultural gaps in scientific exchange through innovative team challenge workshops

Connie M. Lee, Siyuan Gong, Chao Tang, Wendell A. Lim

Journal:

Quantitative Biology

Year:

2013

Language:

english

File:

PDF, 375 KB

english, 2013

16

Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

Toettcher, Jared E., Weiner, Orion D., Lim, Wendell A.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.14 MB

english, 2013

17

Sending Mixed Messages for Cell Population Control

Youk, Hyun, Lim, Wendell A.

Journal:

Year:

2014

Language:

english

File:

PDF, 618 KB

english, 2014

18

An analysis of packing in the protein folding problem

Richards, Frederic M., Lim, Wendell A.

Journal:

Quarterly Reviews of Biophysics

Year:

1993

Language:

english

File:

PDF, 5.42 MB

english, 1993

19

Expanding the CRISPR imaging toolset with Staphylococcus aureus Cas9 for simultaneous imaging of multiple genomic loci

Chen, Baohui, Hu, Jeffrey, Almeida, Ricardo, Liu, Harrison, Balakrishnan, Sanjeev, Covill-Cooke, Christian, Lim, Wendell A., Huang, Bo

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 9.02 MB

english, 2016

20

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

Morsut, Leonardo, Roybal, Kole T., Xiong, Xin, Gordley, Russell M., Coyle, Scott M., Thomson, Matthew, Lim, Wendell A.

Journal:

Year:

2016

Language:

english

File:

PDF, 3.98 MB

english, 2016

21

Modular engineering of cellular signaling proteins and networks

Gordley, Russell M, Bugaj, Lukasz J, Lim, Wendell A

Journal:

Current Opinion in Structural Biology

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

22

Cellular perception and misperception: Internal models for decision-making shaped by evolutionary experience

Mitchell, Amir, Lim, Wendell

Journal:

Year:

2016

Language:

english

File:

PDF, 577 KB

english, 2016

23

Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities

Roybal, Kole T., Lim, Wendell A.

Journal:

Annual Review of Immunology

Year:

2017

Language:

english

File:

PDF, 846 KB

english, 2017

24

Building a Stable Relationship: Ensuring Homeostasis among Cell Types within a Tissue

Frankel, Nicholas W., Lim, Wendell A.

Journal:

Year:

2018

Language:

english

File:

PDF, 413 KB

english, 2018

25

Engineering cell–cell communication networks: programming multicellular behaviors

Toda, Satoshi, Frankel, Nicholas W, Lim, Wendell A

Journal:

Current Opinion in Chemical Biology

Year:

2019

Language:

english

File:

PDF, 2.22 MB

english, 2019

26

Engineering T Cells to Treat Cancer: The Convergence of Immuno-Oncology and Synthetic Biology

Choe, Joseph H., Williams, Jasper Z., Lim, Wendell A.

Journal:

Annual Review of Cancer Biology

Year:

2020

File:

PDF, 860 KB

2020

27

Alterations of human acellular tissue matrix by gamma irradiation: Histology, biomechanical property, stability, in vitro cell repopulation, and remodeling

Sok-Siam Gouk, Tit-Meng Lim, Swee-Hin Teoh, Wendell Q. Sun

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

28

The engineering principles of cellular control and movement systems

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2006

Language:

english

File:

PDF, 101 KB

english, 2006

29

β Strand Peptidomimetics as Potent PDZ Domain Ligands

Ming C. Hammond, Baruch Z. Harris, Wendell A. Lim, Paul A. Bartlett

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 273 KB

english, 2006

30

Stability and peptide binding affinity of an SH3 domain from the Caenorhabditis elegans signaling protein Sem-5

Wendell A. Lim, Robert O. Fox, Frederic M. Richards

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 569 KB

english, 1994

31

Improving SH3 domain ligand selectivity using a non-natural scaffold

Jack T Nguyen, Margaret Porter, Mehran Amoui, W Todd Miller, Ronald N Zuckermann, Wendell A Lim

Journal:

Chemistry & Biology

Year:

2000

Language:

english

File:

PDF, 265 KB

english, 2000

32

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

Lim, Wendell A., Richards, Frederic M., Fox, Robert O.

Journal:

Year:

1994

File:

PDF, 743 KB

1994

33

Build life to understand it

Elowitz, Michael, Lim, Wendell A.

Journal:

Year:

2010

Language:

english

File:

PDF, 308 KB

english, 2010

34

10.1038/77891

Zarrinpar, Ali, Lim, Wendell A.

Journal:

Natural Structural Biology

Year:

2000

Language:

english

File:

PDF, 384 KB

english, 2000

35

10.1038/89586

Prehoda, Kenneth E., Lim, Wendell A.

Journal:

Natural Structural Biology

Year:

2001

Language:

english

File:

PDF, 599 KB

english, 2001

36

Optimization of specificity in a cellular protein interaction network by negative selection

Zarrinpar, Ali, Park, Sang-Hyun, Lim, Wendell A.

Journal:

Year:

2003

Language:

english

File:

PDF, 387 KB

english, 2003

37

Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors

Yeh, Brian J., Rutigliano, Robert J., Deb, Anrica, Bar-Sagi, Dafna, Lim, Wendell A.

Journal:

Year:

2007

Language:

english

File:

PDF, 406 KB

english, 2007

38

The pathogen protein EspFU hijacks actin polymerization using mimicry and multivalency

Sallee, Nathan A., Rivera, Gonzalo M., Dueber, John E., Vasilescu, Dan, Mullins, R. Dyche, Mayer, Bruce J., Lim, Wendell A.

Journal:

Year:

2008

Language:

english

File:

PDF, 609 KB

english, 2008

39

Spatiotemporal control of cell signalling using a light-switchable protein interaction

Levskaya, Anselm, Weiner, Orion D., Lim, Wendell A., Voigt, Christopher A.

Journal:

Year:

2009

Language:

english

File:

PDF, 925 KB

english, 2009

40

Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT

Carlton, Victoria E. H., Harris, Baruch Z., Puffenberger, Erik G., Batta, A. K., Knisely, A. S., Robinson, Donna L., Strauss, Kevin A., Shneider, Benjamin L., Lim, Wendell A., Salen, Gerald

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

41

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

Toettcher, Jared E, Voigt, Christopher A, Weiner, Orion D, Lim, Wendell A

Journal:

Year:

2010

Language:

english

File:

PDF, 679 KB

english, 2010

42

Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function

Yu, Timothy W., Hao, Joe C., Lim, Wendell, Tessier-Lavigne, Marc, Bargmann, Cornelia I.

Journal:

Nature Neuroscience

Year:

2002

Language:

english

File:

PDF, 1.27 MB

english, 2002

43

Designing customized cell signalling circuits

Lim, Wendell A.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2010

Language:

english

File:

PDF, 646 KB

english, 2010

44

Critical residues in an SH3 domain from Sem-5 suggest a mechanism for proline-rich peptide recognition

Lim, Wendell A., Richards, Frederic M.

Journal:

Natural Structural Biology

Year:

1994

File:

PDF, 606 KB

1994

45

How Src exercises self-restraint

Nguyen, Jack T., Lim, Wendell A.

Journal:

Natural Structural Biology

Year:

1997

File:

PDF, 1.04 MB

1997

46

Frederic M Richards 1925–2009

Journal:

Nature Structural and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 765 KB

english, 2009

47

Mutational analysis of protein stability

Robert T. Sauer, Wendell A. Lim

Journal:

Current Biology

Year:

1992

Language:

english

File:

PDF, 117 KB

english, 1992

48

Rewiring cell signaling: the logic and plasticity of eukaryotic protein circuitry

John E Dueber, Brian J Yeh, Roby P Bhattacharyya, Wendell A Lim

Journal:

Current Opinion in Structural Biology

Year:

2004

Language:

english

File:

PDF, 768 KB

english, 2004

49

Docking interactions in protein kinase and phosphatase networks

Attila Reményi, Matthew C Good, Wendell A Lim

Journal:

Current Opinion in Structural Biology

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

50

Scaffolds: interaction platforms for cellular signalling circuits

András Zeke, Melinda Lukács, Wendell A. Lim, Attila Reményi

Journal:

Trends in Cell Biology

Year:

2009

Language:

english

File:

PDF, 1.35 MB

english, 2009

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